Predicting the risk of anastomotic leakage after anterior resection for rectal

Objective To evaluate the risk of anastomotic leakage after anterior resection for rectal. Methods From March 2005 to August 2009, 338 rectal cancer patients who underwent anterior resection of the Department of General Surgery in the Affiliated Changzheng Hospital of Second Military Medical University were selected as the subjects. All patients experienced a total mesorectal excision operation. Univariate and multivariate analysis were performed to determine risk factors for anastomotic leakage. Results The incidence of anastomotic leakage was 9.2%. Univariate analysis and multivariate analysis revealed that age (OR: 3.380, 95%CI: 1.346~8.489), BMI (OR: 11.828, 95%CI: 4.123~33.858), tumor location (OR: 6.304, 95%CI: 162~18.382), and intestinal obstruction (OR: 6.675, 95%CI: 2.164~20.594) were independent factors for anastomotic leakage. Conclusions The incidence of anastomotic leakage after anterior resection of rectum was related to the factors such as gender, age, BMI index, tumor location and intestinal obstruction. For patients with risk factors such as men, advanced age, obesity, low rectal cancer, intestinal obstruction, postoperative anastomotic leakage risk will increase. Key words: Rectal neoplasms; Colorectal surgery; Anastomotic leakage; Total mesorectal excision