2014•Chinese Journal of NeuromedicineRequires access

Recent advance in magnetic resonance imaging in brain lesions of neuromyelitis optica

Cheng Chen

Abstract

视神经脊髓炎(neuromyelitis optica,NMO)是一种严重的中枢神经系统炎性脱髓鞘病变,其临床特点包括反复发作的视神经炎及长节段横贯性脊髓炎(图1A).视神经脊髓炎特异性抗体(NMO-IgG),即水通道蛋白4(aquaporin4,AQP4)抗体,是NMO的标志物,这些临床及免疫学特征已被用于多发性硬化症(multiple sclerosis,MS)和NMO的鉴别.传统观点认为NMO无脑部受累,所以长期以来将发病时视神经外脑内发现病灶的病例排除在NMO诊断之外. 关键词：视神经脊髓炎;脑部病变;磁共振成像分类号：R816.1 文献标识码：A 文章编号：1671-8925(2014)06-0645-04

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Key concepts: Neuromyelitis optica, Magnetic resonance imaging, Nuclear magnetic resonance, Medicine, Physics, Radiology, Multiple sclerosis, Psychiatry