Clinical analysis on metoprolol combined with trimetazidine in the treatment of coronary disease with cardiac failure

Objective To investigate the clinical effects of metoprolol combined with trimetazidine in treating coronary disease with cardiac failure.Methods 122 cases of coronary disease with cardiac failure patients admitted in our hospital from June 2010 to September 2013 were randomly divided into experimental group (72 cases,conventional therapy +metoprolol +trimetazidine) and control group (50 cases,conventional therapy+metoprolol),the efficacy of two groups were compared.Results ① The total efficiency of experimental group (90.28％) was higher than that of control group (76.00％) (P ＜ 0.05) ; ② After 3 months of treatment,the LEVF,LEVDD,LEVSD,6min walking-distance of experimental group were better than those of control group (P ＜ 0.05).Conclusion There is significant effects on metoprolol combined with trimetazidine in treating coronary disease with cardiac failure,which is worthy of clinical use widely. Key words: Metoprolol;  Trimetazidine;  Coronary disease;  Cardiac failure