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The levels of serum interleukin 8 and 10 with jinfants hepatitis syndrome and significance

梅红, 黄静宁, 彭罕鸣

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Abstract

目的探讨婴儿肝炎综合征(婴肝)患儿血清白细胞介素8(IL-8)、IL-10含量变化及临床意义.方法应用ELISA法检测25例婴肝患儿及正常对照组血清IL-8、IL-10含量.结果婴肝患儿血清IL-8含量明显高于正常对照组,差异有显著性.肝功能损害严重者,血清IL-8水平升高更明显.而婴肝患儿血清IL-10含量仅较正常对照组轻度升高,差异无显著性.结论细胞因子在婴肝患儿的发病中起重要作用,其血清IL-8水平有明显升高,且与病情的程度有关;IL-10在婴肝患儿中含量变化不明显.

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目的探讨婴儿肝炎综合征(婴肝)患儿血清白细胞介素8(IL-8)、IL-10含量变化及临床意义.方法应用ELISA法检测25例婴肝患儿及正常对照组血清IL-8、IL-10含量.结果婴肝患儿血清IL-8含量明显高于正常对照组,差异有显著性.肝功能损害严重者,血清IL-8水平升高更明显.而婴肝患儿血清IL-10含量仅较正常对照组轻度升高,差异无显著性.结论细胞因子在婴肝患儿的发病中起重要作用,其血清IL-8水平有明显升高,且与病情的程度有关;IL-10在婴肝患儿中含量变化不明显.

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Available abstract

目的探讨婴儿肝炎综合征(婴肝)患儿血清白细胞介素8(IL-8)、IL-10含量变化及临床意义.方法应用ELISA法检测25例婴肝患儿及正常对照组血清IL-8、IL-10含量.结果婴肝患儿血清IL-8含量明显高于正常对照组,差异有显著性.肝功能损害严重者,血清IL-8水平升高更明显.而婴肝患儿血清IL-10含量仅较正常对照组轻度升高,差异无显著性.结论细胞因子在婴肝患儿的发病中起重要作用,其血清IL-8水平有明显升高,且与病情的程度有关;IL-10在婴肝患儿中含量变化不明显.

Key concepts: Medicine, Immunology, Hepatitis, Interleukin, Virology, Cytokine

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