Status and role of theophylline in chronic obstructive pulmonary disease
Hongjian Su, Qiuyue Wang
Abstract
Hongjian Su, Qiuyue Wang
Abstract
Theophylline, as a bronchodilator medication, is cheap and convenient. But its clinical application is limited,because that its therapeutic ratio is small and most of the benefit occurs only when near-toxic doses are given. Recent years, research have shown that low-dose theophylline also has antiinflammatory and immune regulatory role, which provided a new theoretical evidence for theophylline in the treatment of chronic obstructive pulmonary disease. Key words: Theophylline; Chronic obstructive pulmonary disease
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Theophylline, as a bronchodilator medication, is cheap and convenient. But its clinical application is limited,because that its therapeutic ratio is small and most of the benefit occurs only when near-toxic doses are given. Recent years, research have shown that low-dose theophylline also has antiinflammatory and immune regulatory role, which provided a new theoretical evidence for theophylline in the treatment of chronic obstructive pulmonary disease. Key words: Theophylline; Chronic obstructive pulmonary disease
Key concepts: Theophylline, Medicine, Bronchodilator, Pulmonary disease, Intensive care medicine, COPD, Disease, Asthma