2019•国际医药卫生导报Requires access
Effects of inhalation and intravenous anesthesia with sevoflurane versus total intravenous anesthesia on recovery of patients undergoing partial hepatic resection
Mingjie Han
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Abstract
Objective
To investigate the effects of inhalation and intravenous anesthesia with sevoflurane versus total intravenous anesthesia on recovery of patients undergoing partial hepatic resection.
Methods
Fifty ASA I or Ⅱ patients undergoing partial hepatic resection were allocated randomly into two group A and group B. After induction, general anesthesia was maintained with sevoflurane (0.3~0.5 MAC), propofol (1.5~3.0 μg/ml target plasma concentration) and remifentanil (2.0~8.0 ng/ml target plasma concentration) in group A and propofol (3.0~6.0 μg/ml target plasma concentration), remifentanil (2.0~8.0 ng/ml target plasma concentration) in group B. The times for respiration recovery, awakening, and extubation, as well as bucking response, were recorded. The Sedation-Agitation Scale and pain score were also noted 1 (T1), 5 (T2), 10 (T3), 20 (T4), 30 (T5), and 40 min (T6) after extubation.
Results
The times for respiration recovery, awakening, and extubation in group A were shorter than those in group B [(8.0±3.5) mim vs. (15.0±5.2) min, (13.0±4.8) min vs. (20.6±6.0) min, and (14.7±5.1) mim vs. (22.4±7.1) min; all P<0.05]. The incidence of bucking response was higher in group A than in group B (60.0% vs. 20.0%, P<0.05).
Conclusion
Inhalation and intravenous anesthesia with sevoflurane can decrease the times of respiration recovery, extubating, and awakening; and total intravenous anesthesia can lower the incidence of bucking response in patients with partial hepatic resection.
Key words:
Sevoflurane; Inhalation and intravenous anesthesia; Total intravenous anesthesia; Hepatic resection