2019Central Plains Medical JournalRequires access

Infusion methods of immune enteral nutrition for patients with gastric cancer after operation

Feng Lu, Jingrong Zhou, Lei Qiu, Xiuwei H. Yang, Yongchang Miao

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Abstract

Objective To investigate the infusion methods of immune enteral nutrition for patients with gastric cancer after operation. Methods Ninety-seven patients with gastric cancer admitted to the Second People’s Hospital of Lianyungang from January 2017 to December 2018 were selected as the study subjects. According to random number table method, patients were randomly divided into observation group (49 cases) and control group (48 cases). Patients in observation group were given continuous immune enteral nutrition, while patients in control group were given periodic immune enteral nutrition. The changes of enteral nutrition infusion, nutritional and immune indexes before and after operation were compared between the two groups. Results Three patients showed immune enteral nutrition intolerance in control group, and the patients in observation group were tolerant to nutrition supply (P 0.05). IgA and CD4/CD8 in observation group on 7th day were (2.9±0.5)g/L and 2.2±0.5, respectively, which were significantly higher than those in control group, which were (2.6±0.7)g/L and 2.0±0.6, respectively, and the difference was statistically significant (t=2.706, 2.101; all P 0.05). Conclusions Compared with periodic infusion, continuous infusion of immune enteral nutrition can reduce the nutrition intolerance, shorten the time of transition to total enteral nutrition and extubation after gastric cancer surgery, which has less influence on the nutritional indexes of gastric cancer patients. It can improve the immune function of the body and is worthy of clinical application. Key words: Immune enteral nutrition; Gastric cancer; Postoperative; Infusion methods

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Objective To investigate the infusion methods of immune enteral nutrition for patients with gastric cancer after operation. Methods Ninety-seven patients with gastric cancer admitted to the Second People’s Hospital of Lianyungang from January 2017 to December 2018 were selected as the study subjects. According to random number table method, patients were randomly divided into observation group (49 cases) and control group (48 cases). Patients in observation group were given continuous immune enteral nutrition, while patients in control group were given periodic immune enteral nutrition. The changes of enteral nutrition infusion, nutritional and immune indexes before and after operation were compared between the two groups. Results Three patients showed immune enteral nutrition intolerance in control group, and the patients in observation group were tolerant to nutrition supply (P 0.05). IgA and CD4/CD8 in observation group on 7th day were (2.9±0.5)g/L and 2.2±0.5, respectively, which were significantly higher than those in control group, which were (2.6±0.7)g/L and 2.0±0.6, respectively, and the difference was statistically significant (t=2.706, 2.101; all P 0.05). Conclusions Compared with periodic infusion, continuous infusion of immune enteral nutrition can reduce the nutrition intolerance, shorten the time of transition to total enteral nutrition and extubation after gastric cancer surgery, which has less influence on the nutritional indexes of gastric cancer patients. It can improve the immune function of the body and is worthy of clinical application. Key words: Immune enteral nutrition; Gastric cancer; Postoperative; Infusion methods

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Available abstract

Objective To investigate the infusion methods of immune enteral nutrition for patients with gastric cancer after operation. Methods Ninety-seven patients with gastric cancer admitted to the Second People’s Hospital of Lianyungang from January 2017 to December 2018 were selected as the study subjects. According to random number table method, patients were randomly divided into observation group (49 cases) and control group (48 cases). Patients in observation group were given continuous immune enteral nutrition, while patients in control group were given periodic immune enteral nutrition. The changes of enteral nutrition infusion, nutritional and immune indexes before and after operation were compared between the two groups. Results Three patients showed immune enteral nutrition intolerance in control group, and the patients in observation group were tolerant to nutrition supply (P 0.05). IgA and CD4/CD8 in observation group on 7th day were (2.9±0.5)g/L and 2.2±0.5, respectively, which were significantly higher than those in control group, which were (2.6±0.7)g/L and 2.0±0.6, respectively, and the difference was statistically significant (t=2.706, 2.101; all P 0.05). Conclusions Compared with periodic infusion, continuous infusion of immune enteral nutrition can reduce the nutrition intolerance, shorten the time of transition to total enteral nutrition and extubation after gastric cancer surgery, which has less influence on the nutritional indexes of gastric cancer patients. It can improve the immune function of the body and is worthy of clinical application. Key words: Immune enteral nutrition; Gastric cancer; Postoperative; Infusion methods

Key concepts: Parenteral nutrition, Medicine, Enteral administration, Immune system, Gastroenterology, Internal medicine, Cancer, Immunology

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