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2013•Guoji zhongliuxue zazhiRequires access

Adoptive cellular immunotherapy for cancer

Yiman Shang, Zi-Bing Wang, Yijie Ma, Yong Zhang, Quanli Gao

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Abstract

Adoptive cellular immunotherapy (ACI) achieves the elimination and control of tumor by mobilizing the body's immune function.It also has targeted efficacy and mild untoward effects.Cytokineinduced killer cells and tumor-infiltrating lymphocytes have been widely used in clinic and have obtained preliminary efficacy.With the development and clinical application of the specific gene transfer of T cell,it will further increase the efficacy of immunotherapy.At present,improving cell culture technology and cell function and using with other treatment are the key links to improve the efficacy of ACI. Key words: Neoplasms;  Immunotherapy;  Killer cells

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What this paper is about

Adoptive cellular immunotherapy (ACI) achieves the elimination and control of tumor by mobilizing the body's immune function.It also has targeted efficacy and mild untoward effects.Cytokineinduced killer cells and tumor-infiltrating lymphocytes have been widely used in clinic and have obtained preliminary efficacy.With the development and clinical application of the specific gene transfer of T cell,it will further increase the efficacy of immunotherapy.At present,improving cell culture technology and cell function and using with other treatment are the key links to improve the efficacy of ACI. Key words: Neoplasms;  Immunotherapy;  Killer cells

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Available abstract

Adoptive cellular immunotherapy (ACI) achieves the elimination and control of tumor by mobilizing the body's immune function.It also has targeted efficacy and mild untoward effects.Cytokineinduced killer cells and tumor-infiltrating lymphocytes have been widely used in clinic and have obtained preliminary efficacy.With the development and clinical application of the specific gene transfer of T cell,it will further increase the efficacy of immunotherapy.At present,improving cell culture technology and cell function and using with other treatment are the key links to improve the efficacy of ACI. Key words: Neoplasms;  Immunotherapy;  Killer cells

Key concepts: Adoptive immunotherapy, Immunotherapy, Immune system, Clinical efficacy, Medicine, Adoptive cell transfer, Cancer immunotherapy, Immunology

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