Application of photosensitizer drug delivery system in photodynamic therapy of tumors
Qingfeng Tu, Xiuli Wang, Lei Shi
Abstract
Qingfeng Tu, Xiuli Wang, Lei Shi
Abstract
In vitro or in vivo results of investigations into the development of photosensitizer drug delivery systems have demonstrated that the use of vehicles not only enhance the stability of photosensitizer,but also promote the accumulation of photosensitizer in tumor tissue,enhance the targetability of photodynamic therapy,the working depth,the yield of singlet oxygen and overcome many untoward effects.So the research of new photosensitizer drug delivery system has important application value in photodynamic therapy of tumor. Key words: Photodynamic therapy; Photosensitizer; Drug carriers; Neoplasms
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In vitro or in vivo results of investigations into the development of photosensitizer drug delivery systems have demonstrated that the use of vehicles not only enhance the stability of photosensitizer,but also promote the accumulation of photosensitizer in tumor tissue,enhance the targetability of photodynamic therapy,the working depth,the yield of singlet oxygen and overcome many untoward effects.So the research of new photosensitizer drug delivery system has important application value in photodynamic therapy of tumor. Key words: Photodynamic therapy; Photosensitizer; Drug carriers; Neoplasms
Key concepts: Photosensitizer, Photodynamic therapy, Singlet oxygen, Drug, In vivo, Drug delivery, Pharmacology, Chemistry