Preliminary study on evaluating volume changes in left atrial remodeling and left ventricular remodeling by three-dimensional echocardiography with automatic quantification

Objective To discuss the feasibility and reproducibility of left ventricular volume and function of patients with left atrial remodeling and left ventricular remodeling by 3-dimensional echocardiography HeartModel(3D-HM). Methods Three-dimensional images of 156 subjects were collected under HMACQ imaging mode. They were assigned into three groups: ① control group (group A, n=70); ② group of left ventricular remodeling after , acute myocardial infarction (group B, n=17); ③ group of hypertension left atrial remodeling (group C, n=69). 3D-HM method was used for quantifying left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), left atrial end-systolic volume (LAESV) and left ventricular ejection fraction (LVEF), and the results were compared with conventional 3D-manual results. The reproducibility of the 3D-HM method within one group and among different groups was evaluated. Results There was a significant difference in all the parameters measured with the 3D-HM method in different groups(P 0.05). Conclusions 3D-HM is a fast and feasible technique with high reproducibility for quantifying the left ventricular volume and function in patients with left atrial remodeling and left ventricular remodeling. Key words: Echocardiography, real-time three-dimensional; Ventricular remodeling; Ventricular function, left; Atrial function, left