Observate the efficacy of alprostadil combined with edaravone treatment on infarction

Objective To investigate the clinical efficacy and feasibility of alprostaudil and edaravone on cerebral infarction.Methods Seventy-eight cases of cerebral infarction were randomly divided into experimental group and control group.The patients of control group were treated with compound Danshen injection and citicoline injection conventional therapy.On this basis,the patients of experimental group were given alprostadil and edaravone.Then,the neurological deficit score(NDS),ADL and clinical effect of the two groups were compared.Results Before treatment,the NDS and ADL scores of the two groups had no significant difference (P ＞ 0.05),after 14 days of treatment,the indicators of two groups significantly improved (P ＜ 0.05),but two indicators of magnitude improvement in the experimental group patients were significantly greater than the control group (P ＜ 0.05).After 14 days of treatment,the total effective rate of the experimental group was 95.0％,it was far higher than the control group(76.3％) (P ＜ 0.05).The experimental group had 3 cases of patients with complications,less than that in the control group(7 cases) (P ＜ 0.05).Conclusions Alprostadil combine with edaravone has exact clinical efficacy on cerebral infarction.It can effectively alleviate the degree of neurological deficit and improve the ability of daily lives. Key words: Alprostadil ;  Edaravone ;  Infarction ;  Efficacy