2018•Int J Endocrinol MetabRequires access

Expression and function of miRNA in thyroid carcinoma

Beining Zhang, Ruyi Yan, Jinlian Zhou

Abstract

microRNA is a class of single-stranded, non-coding small molecule RNA that is highly conserved and endogenous, which is matched to the target gene mRNA base, thus regulating the expression of the target gene at post-transcriptional levels. In recent years, several studies have found that miRNA dysregulated expressed in different types of thyroid carcinoma, and indicated that miRNA might play important roles in the occurrence and development of thyroid carcinoma. Key words: Thyroid carcinoma; MicroRNA

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Key concepts: microRNA, Thyroid carcinoma, Biology, Gene, Gene expression, Thyroid, Endogeny, Messenger RNA