2010•Zhongguo linchuang shiyong yixueRequires access

Acarbose insulin glargine combined on treatment of elderly diabetic

Minggang Wang

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Abstract

Objective To investigate insulin glargine combined acarbose treatment of senile diabetes therapy. Methods 246 cases type 2 diabetes were treated in out - patient or in hospital from January 2008 to January 2010 who were randomly divided into treatment group( 126 ) and control group (120). Treatment group patients treated with insulin glargine combined acarbose treatment, and control group were treated by Protamine zinc mixed recombinant human insulin injection treatment;To observe clinical effects and β -cell function. Results Comparison of two groups of blood glucose time, P < 0. 05; Two groups of insulin daily dose, the incidence of hypoglycemia,P < 0. 01 ;Treatment before and after the C peptide + insulin release test comparison, P < 0. 05; Conclusion Insulin glargine combined acarbose can achieve good control of blood glucose and reducing insulin dosage, reducing the incidence of low blood sugar, which an improvement of β cell function. It is a good drug compliance and treatment program in elderly type 2 diabetes. Key words: Insulin glargine combined acarbose; Senile diabetes; Efficacy

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What this paper is about

Objective To investigate insulin glargine combined acarbose treatment of senile diabetes therapy. Methods 246 cases type 2 diabetes were treated in out - patient or in hospital from January 2008 to January 2010 who were randomly divided into treatment group( 126 ) and control group (120). Treatment group patients treated with insulin glargine combined acarbose treatment, and control group were treated by Protamine zinc mixed recombinant human insulin injection treatment;To observe clinical effects and β -cell function. Results Comparison of two groups of blood glucose time, P < 0. 05; Two groups of insulin daily dose, the incidence of hypoglycemia,P < 0. 01 ;Treatment before and after the C peptide + insulin release test comparison, P < 0. 05; Conclusion Insulin glargine combined acarbose can achieve good control of blood glucose and reducing insulin dosage, reducing the incidence of low blood sugar, which an improvement of β cell function. It is a good drug compliance and treatment program in elderly type 2 diabetes. Key words: Insulin glargine combined acarbose; Senile diabetes; Efficacy

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Available abstract

Objective To investigate insulin glargine combined acarbose treatment of senile diabetes therapy. Methods 246 cases type 2 diabetes were treated in out - patient or in hospital from January 2008 to January 2010 who were randomly divided into treatment group( 126 ) and control group (120). Treatment group patients treated with insulin glargine combined acarbose treatment, and control group were treated by Protamine zinc mixed recombinant human insulin injection treatment;To observe clinical effects and β -cell function. Results Comparison of two groups of blood glucose time, P < 0. 05; Two groups of insulin daily dose, the incidence of hypoglycemia,P < 0. 01 ;Treatment before and after the C peptide + insulin release test comparison, P < 0. 05; Conclusion Insulin glargine combined acarbose can achieve good control of blood glucose and reducing insulin dosage, reducing the incidence of low blood sugar, which an improvement of β cell function. It is a good drug compliance and treatment program in elderly type 2 diabetes. Key words: Insulin glargine combined acarbose; Senile diabetes; Efficacy

Key concepts: Acarbose, Medicine, Insulin glargine, Insulin, Hypoglycemia, Postprandial, Internal medicine, Blood sugar

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