2007Zhongguo jiceng yiyaoRequires access

Study on expression of CA153,CEA and its clinical significance in the patients with breast cancer

Jun Yang

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Abstract

目的 探讨乳腺癌患者血清糖类抗原153(CA153)和癌胚抗原(CEA)表达及临床意义.方法 利用全自动快速粒子酶免疫分析系统,检测30例健康人、52例乳腺良性疾病和208例乳腺癌患者血清CA153和CEA的水平,分析CA153和CEA检测值与乳腺癌临床特征之间的关系.结果 乳腺癌患者治疗前血清CA153及CEA的水平明显高于治疗后的水平(P<0.001),初诊初治及复发转移患者的血清CA153及CEA的水平明显高于乳腺良性病变和健康人群(P<0.001);联合检测可以提高对乳腺癌诊断的阳性率.结论 联合检测CA153及CEA水平可以提高对乳腺癌诊断的敏感性和准确性,并可用于该肿瘤的预后判断。

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目的 探讨乳腺癌患者血清糖类抗原153(CA153)和癌胚抗原(CEA)表达及临床意义.方法 利用全自动快速粒子酶免疫分析系统,检测30例健康人、52例乳腺良性疾病和208例乳腺癌患者血清CA153和CEA的水平,分析CA153和CEA检测值与乳腺癌临床特征之间的关系.结果 乳腺癌患者治疗前血清CA153及CEA的水平明显高于治疗后的水平(P<0.001),初诊初治及复发转移患者的血清CA153及CEA的水平明显高于乳腺良性病变和健康人群(P<0.001);联合检测可以提高对乳腺癌诊断的阳性率.结论 联合检测CA153及CEA水平可以提高对乳腺癌诊断的敏感性和准确性,并可用于该肿瘤的预后判断。

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Available abstract

目的 探讨乳腺癌患者血清糖类抗原153(CA153)和癌胚抗原(CEA)表达及临床意义.方法 利用全自动快速粒子酶免疫分析系统,检测30例健康人、52例乳腺良性疾病和208例乳腺癌患者血清CA153和CEA的水平,分析CA153和CEA检测值与乳腺癌临床特征之间的关系.结果 乳腺癌患者治疗前血清CA153及CEA的水平明显高于治疗后的水平(P<0.001),初诊初治及复发转移患者的血清CA153及CEA的水平明显高于乳腺良性病变和健康人群(P<0.001);联合检测可以提高对乳腺癌诊断的阳性率.结论 联合检测CA153及CEA水平可以提高对乳腺癌诊断的敏感性和准确性,并可用于该肿瘤的预后判断。

Key concepts: Medicine, Breast cancer, Internal medicine, Oncology, Clinical significance, Cancer, Gastroenterology

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