2014•Guoji zhongliuxue zazhiRequires access

Anticancer mechanism of salinomycin

Ying Lü, W. F. Mader, Jun Mao, Lianhong Li

Abstract

Salinomycin is a chemotherapeutic drug commonly used to inhibit the growth of tumor and specifically kill the cancer stem cells (CSC).The anti-cancer effect of salinomycin has attracted extensive attention at home and abroad,whihc is realized by inducing cancer cell apoptosis,suppressing cancer cell proliferation and invasion and reducing drug resistance. Key words: Neoplasms ; Neoplastic stem cells ; Salinomycin

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Key concepts: Salinomycin, Cancer stem cell, Stem cell, Apoptosis, Cancer research, Cancer, Cancer cell, Drug