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Relationship between cladribine (CDA) plasma, intracellular cladribine-5-triphosphate (CDATP) concentration, deoxycytidine kinase (DCK) and chemotherapeutic activity in chronic lymphocytic leukemia (CLL)

Freidoun Albertioni, Synnöve Lindemalm, Staffan Eriksson, Gunnar Juliusson, Jan Liliemark

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Key concepts: Chemistry, Superoxide, Cladribine, Deoxycytidine kinase, Hydrogen peroxide, Chronic lymphocytic leukemia, Enzyme, Intracellular

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Relationship between cladribine (CDA) plasma, intracellular cladribine-5-triphosphate (CDATP) concentration, deoxycytidine kinase (DCK) and chemotherapeutic activity in chronic lymphocytic leukemia (CLL) — Research Paper | ScholarLens