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2015•Guoji shuxue ji xueyexue zazhiRequires access

Research progress of cladribine in chronic lymphocytic leukemia

Meilin Cao

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Abstract

Cladribine is a purine analogue, which is used in treatment of multiple sclerosis and hairy cell leukemia. Recently, more and more studies have shown that cladribine is a good anti-tumor choice for chronic lymphocytic leukemia (CLL). Clinical trials results show that either use alone or in combination with other drugs in patients with CLL, cladribine has shown good effect. This article focuses on the research progress of cladribine in CLL, in order to provide references for clinical medication in CLL treatment. Key words: Cladribine; Leukemia, lymphocytic, chronic, B-cell; Purine analog

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What this paper is about

Cladribine is a purine analogue, which is used in treatment of multiple sclerosis and hairy cell leukemia. Recently, more and more studies have shown that cladribine is a good anti-tumor choice for chronic lymphocytic leukemia (CLL). Clinical trials results show that either use alone or in combination with other drugs in patients with CLL, cladribine has shown good effect. This article focuses on the research progress of cladribine in CLL, in order to provide references for clinical medication in CLL treatment. Key words: Cladribine; Leukemia, lymphocytic, chronic, B-cell; Purine analog

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Available abstract

Cladribine is a purine analogue, which is used in treatment of multiple sclerosis and hairy cell leukemia. Recently, more and more studies have shown that cladribine is a good anti-tumor choice for chronic lymphocytic leukemia (CLL). Clinical trials results show that either use alone or in combination with other drugs in patients with CLL, cladribine has shown good effect. This article focuses on the research progress of cladribine in CLL, in order to provide references for clinical medication in CLL treatment. Key words: Cladribine; Leukemia, lymphocytic, chronic, B-cell; Purine analog

Key concepts: Cladribine, Chronic lymphocytic leukemia, Purine analogue, Medicine, Hairy cell leukemia, Leukemia, Oncology, Immunology

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