2019•PubMedRequires access

Acinic cell carcinoma of the parotid gland: A diagnostic dilemma on cytology.

Abhimanyu Sharma, Sana Ahuja, Preeti Diwaker, Neelam Wadhwa, V K Arora

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Abstract

INTRODUCTION: Acinic cell carcinoma (ACC) represents 1-6% of parotid gland neoplasms. CASE REPORT: We report cytomorphological features of two uncommon variants of acinic cell carcinoma. The first case was an eleven-year-old female with a nodular mass in parotid and the FNA smears demonstrated a lymphoepithelial lesion composed of epithelial tumour cells with features of acinar cells in a lymphoid background. The second case was a 62-year-old male with a large parotid mass. The FNA smears revealed presence of extracellular, acellular amyloid-like material with tumour cells arranged in follicles. DISCUSSION: Awareness of cytomorphological features of these unusual variants of acinic cell carcinoma may help to avoid diagnostic pitfall.

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INTRODUCTION: Acinic cell carcinoma (ACC) represents 1-6% of parotid gland neoplasms. CASE REPORT: We report cytomorphological features of two uncommon variants of acinic cell carcinoma. The first case was an eleven-year-old female with a nodular mass in parotid and the FNA smears demonstrated a lymphoepithelial lesion composed of epithelial tumour cells with features of acinar cells in a lymphoid background. The second case was a 62-year-old male with a large parotid mass. The FNA smears revealed presence of extracellular, acellular amyloid-like material with tumour cells arranged in follicles. DISCUSSION: Awareness of cytomorphological features of these unusual variants of acinic cell carcinoma may help to avoid diagnostic pitfall.

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Available abstract

INTRODUCTION: Acinic cell carcinoma (ACC) represents 1-6% of parotid gland neoplasms. CASE REPORT: We report cytomorphological features of two uncommon variants of acinic cell carcinoma. The first case was an eleven-year-old female with a nodular mass in parotid and the FNA smears demonstrated a lymphoepithelial lesion composed of epithelial tumour cells with features of acinar cells in a lymphoid background. The second case was a 62-year-old male with a large parotid mass. The FNA smears revealed presence of extracellular, acellular amyloid-like material with tumour cells arranged in follicles. DISCUSSION: Awareness of cytomorphological features of these unusual variants of acinic cell carcinoma may help to avoid diagnostic pitfall.

Key concepts: Acinic cell carcinoma, Pathology, Parotid gland, Medicine, Cytology, Carcinoma, Mucoepidermoid carcinoma

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