Well-differentiated acinic cell carcinoma with lymphoid stroma associated with osteoclast-like giant cells of the parotid gland in children: a case report and literature review.
Zhengjin Liu, Chao Pan, Ping Yin, Hongfeng Liao
Abstract
Zhengjin Liu, Chao Pan, Ping Yin, Hongfeng Liao
Abstract
Acinic cell carcinoma of the parotid gland in children rarely occurs. Well-differentiated acinic cell carcinoma with lymphoid stroma is a subtype hardly seen but has a better prognosis than conventional acinic cell carcinoma. We hereby report a previously unreported case of a 9-year-old Chinese girl with well-differentiated acinic cell carcinoma with lymphoid stroma associated with osteoclast-like giant cells of the parotid gland. The pathology, diagnosis, presentation, management, and the clinical outcome are discussed and the literature is reviewed.
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Acinic cell carcinoma of the parotid gland in children rarely occurs. Well-differentiated acinic cell carcinoma with lymphoid stroma is a subtype hardly seen but has a better prognosis than conventional acinic cell carcinoma. We hereby report a previously unreported case of a 9-year-old Chinese girl with well-differentiated acinic cell carcinoma with lymphoid stroma associated with osteoclast-like giant cells of the parotid gland. The pathology, diagnosis, presentation, management, and the clinical outcome are discussed and the literature is reviewed.
Key concepts: Acinic cell carcinoma, Stroma, Pathology, Parotid gland, Salivary gland, Giant cell, Biology, Carcinoma