2018•PubMedOpen access

Well-differentiated acinic cell carcinoma with lymphoid stroma associated with osteoclast-like giant cells of the parotid gland in children: a case report and literature review.

Zhengjin Liu, Chao Pan, Ping Yin, Hongfeng Liao

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Abstract

Acinic cell carcinoma of the parotid gland in children rarely occurs. Well-differentiated acinic cell carcinoma with lymphoid stroma is a subtype hardly seen but has a better prognosis than conventional acinic cell carcinoma. We hereby report a previously unreported case of a 9-year-old Chinese girl with well-differentiated acinic cell carcinoma with lymphoid stroma associated with osteoclast-like giant cells of the parotid gland. The pathology, diagnosis, presentation, management, and the clinical outcome are discussed and the literature is reviewed.

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What this paper is about

Acinic cell carcinoma of the parotid gland in children rarely occurs. Well-differentiated acinic cell carcinoma with lymphoid stroma is a subtype hardly seen but has a better prognosis than conventional acinic cell carcinoma. We hereby report a previously unreported case of a 9-year-old Chinese girl with well-differentiated acinic cell carcinoma with lymphoid stroma associated with osteoclast-like giant cells of the parotid gland. The pathology, diagnosis, presentation, management, and the clinical outcome are discussed and the literature is reviewed.

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Available abstract

Acinic cell carcinoma of the parotid gland in children rarely occurs. Well-differentiated acinic cell carcinoma with lymphoid stroma is a subtype hardly seen but has a better prognosis than conventional acinic cell carcinoma. We hereby report a previously unreported case of a 9-year-old Chinese girl with well-differentiated acinic cell carcinoma with lymphoid stroma associated with osteoclast-like giant cells of the parotid gland. The pathology, diagnosis, presentation, management, and the clinical outcome are discussed and the literature is reviewed.

Key concepts: Acinic cell carcinoma, Stroma, Pathology, Parotid gland, Salivary gland, Giant cell, Biology, Carcinoma

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Well-differentiated acinic cell carcinoma with lymphoid stroma associated with osteoclast-like giant cells of the parotid gland in children: a case report and literature review. — Research Paper | ScholarLens