[Analysis of coagulation related parameters between patients with advanced schistosomiasis cirrhosis and hepatitis B cirrhosis].

OBJECTIVE: To analyze the differences of coagulation parameters between patients with advanced schistosomiasis cirrhosis and hepatitis B cirrhosis under different degrees of liver function, so as to provide the evidence for further guidance of judging clinical condition and prognosis. METHODS: Sixty-three patients with advanced schistosomiasis cirrhosis and eighty patients with hepatitis B induced cirrhosis hospitalized in Jingzhou Central Hospital from January 2014 to June 2016 were served as an advanced schistosomiasis cirrhosis group and a hepatitis B cirrhosis group, respectively, and ninety-six gastropathy patients excluded from other diseases that might affect coagulation in the same period were served as a control group. The levels of PT, INR, Fib, TT, APTT, and PLT of the patients among the above 3 groups and the cirrhosis patients with different Child-Pugh classes were detected and compared. RESULTS: > 0.05). CONCLUSIONS: There exist differences of the damage degrees of coagulation function between the patients with advanced schistosomiasis cirrhosis and hepatitis B cirrhosis. When the damage degree of the liver function is lighter, the coagulation function in the patients with hepatitis B cirrhosis decreases more significantly; when the damage degree becomes more severe, APPT in the patients with hepatitis B cirrhosis extends more significantly, while the differences of PLT and PT between them are little.