2020•Cellular and Molecular ImmunologyOpen access

PD-1 blockade-unresponsive human tumor-infiltrating CD8+ T cells are marked by loss of CD28 expression and rescued by IL-15

Kyung Hwan Kim, Hong Kwan Kim, Hyung‐Don Kim, Chang Gon Kim, Hoyoung Lee, Ji Won Han, Seong Jin Choi, Seongju Jeong, Minwoo Jeon, Hyunglae Kim, Jiae Koh, Bo Mi Ku, Su‐Hyung Park, Myung‐Ju Ahn, Eui‐Cheol Shin

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Key concepts: Blockade, CD28, CD8, Cytotoxic T cell, Expression (computer science), Cancer research, Tumor-infiltrating lymphocytes, Cell biology