Prophylactic Effect of Miosis against Early Intraocular Pressure Elevation after V4c Phakic Intraocular Lens Implantation

Purpose: To confirm the prophylactic effect of miosis against intraocular pressure (IOP) early after V4c phakicintraocular lens (ICL) implantation.Design: Interventional case series.Participants: Forty-six myopia patients scheduled for ICL implantation.Methods: This study was performed in 2 stages. In stage 1 (58 eyes of 29 patients), miosis was conductedimmediately postoperative in left eyes, whereas right eyes remained untreated. IOP was compared between rightand left eyes at postoperative hours 1, 2, 6, 12 and 24. In stage 2 (34 eyes of 17 patients), miosis was firstconducted immediately postoperative in left eyes, and IOP, anterior chamber depth (ACD), angle-opening distance(AOD) and trabecular-iris angle (TIA) were measured in both eyes (right/left eye pupil diameter (PD)=7 ± 0.5/3 ± 0.5mm). Second, miosis (right) or mydriasis (left) was conducted and these indicators were observed when PDdecreased to 3 ± 0.5 mm (right) or increased to 7 ± 0.5 mm (left).Results: In stage 1, IOP was significantly higher in right eyes at postoperative hours 1, 2, 6 and 12 (p<0.01). Theprevalence of ocular hypertension was significantly different (Purpose to confirm the prophylactic effect of miosisagainst intraocular pressure (IOP) early after V4c phakic intraocular lens (ICL) implantation.Conclusion: Miosis lowered postoperative IOP early after V4c ICL implantation, possibly due to a more openangle.