2020•Bioorganic & Medicinal ChemistryOpen access

The ability of a triplex-forming oligonucleotide to recognize T-A and C-G base pairs in a DNA duplex is enhanced by incorporating N-acetyl-2,7-diaminoquinoline

Akihiro Ohkubo, Tatsuya Ohnishi, Shuhei Nishizawa, Yuri Nishimura, Shugo Hisamatsu

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Key concepts: Chemistry, Oligonucleotide, Pyrimidine, DNA, Duplex (building), Base pair, Selectivity, Stereochemistry

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The ability of a triplex-forming oligonucleotide to recognize T-A and C-G base pairs in a DNA duplex is enhanced by incorporating N-acetyl-2,7-diaminoquinoline — Research Paper | ScholarLens