2002Chinese Journal of Applied ChemistryRequires access

Synthesis of Mercaptoalkoxy quinoline Compounds

Ke Zheng

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Abstract

Two ω-mercaptoalkoxy quinoline compounds:6-(ω-mercaptodecoxy)-quinoline and 2-(ω-mercaptodecoxy)-4-methyl-quinoline were succesfully synthesized by reacting quinoline with 1,10- dibromodecane and thiourea in alkaline solution. The intermediates and products were characterized by IR, 1H NMR and MS.

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What this paper is about

Two ω-mercaptoalkoxy quinoline compounds:6-(ω-mercaptodecoxy)-quinoline and 2-(ω-mercaptodecoxy)-4-methyl-quinoline were succesfully synthesized by reacting quinoline with 1,10- dibromodecane and thiourea in alkaline solution. The intermediates and products were characterized by IR, 1H NMR and MS.

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Available abstract

Two ω-mercaptoalkoxy quinoline compounds:6-(ω-mercaptodecoxy)-quinoline and 2-(ω-mercaptodecoxy)-4-methyl-quinoline were succesfully synthesized by reacting quinoline with 1,10- dibromodecane and thiourea in alkaline solution. The intermediates and products were characterized by IR, 1H NMR and MS.

Key concepts: Quinoline, Chemistry, Thiourea, Organic chemistry, Medicinal chemistry, Combinatorial chemistry

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