2017•Journal of Pharmacognosy and PhytochemistryRequires access
Evaluation of antipyretic, anti-inflammatory and analgesic activities of various leaf extracts of Kigelia africana
Harpreet Singh, VK Dumka, Rashmi Sagar, Varun Kumar
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Abstract
Present investigation was done on 50 Albino Wistar rats of either sex. Various extracts of Kigelia africana i.e aqueous, alcoholic, acetone and chloroform were evaluated for antipyretic property, anti-inflammatory activity using carrageenan induced paw edema and analgesic activity by tail flick method. Alcoholic extract @ 50 mg/kg showed decrease in temperature after one hour. Aqueous extract @ 100 mg/kg and alcoholic extract @ 50 mg/kg showed significant anti-inflammatory activity whereas significant analgesic activity was shown by aqueous and alcoholic group.