Effect of functional compound recipe liquid of eliminating lead on eliminating lead and calcium in rats.

The experiment was conducted to approve the efficacy of functional compound recipe liquid of eliminating lead and calcium to eliminate lead in rats.Total 120 rats were divided into six groups according to weight: blank group (CK),negative group (ND),positive group (PD) and high group (HD,6.67 Mg·kg -1·BW·d -1 ),middle group (MD,3.33 Mg·kg -1·BW·d -1 ) and low group (LD,1.67 Mg·kg -1·BW·d -1 three groups).Except CK,other groups were drunk 0.24% Pb(AC) 2 ,in which rats were filled with functional compound recipe liquid to eliminate lead and DSMA was added to positive group (PD).On the 20th day,the blood was collected from the tail.on the 40th day,the whole blood was collected from eyeball.After executed,liver and blood were collected to determine the content of lead and calcium.Results showed that lead contents in blood and liver of three dosage groups obviously decreased compared with ND and there was significant difference between any two groups of three dosage groups (P0.01).Meanwhile,the calcium concentration increased in three dosage groups.It is concluded that the functional compound recipe liquid of eliminating lead has the evident function of eliminating lead and can promote calcium absorption.