Degradation and biocompatibility behaviors of fully covered biodegradable polydioxanone biliary stent for human body

This paper presents a study of the degradation and biocompatibility behaviors of fully covered biodegradable polydioxanone biliary stents (FCBPBSs) developed for human body. To investigate the relationship between the mechanical property of FCBPBSs and degradation time, nine FCBPBSs were prepared both by braid-hand method using a self-made cylinder of copper pipe mold and electrospinning. Meanwhile, the response of quality of FCBPBSs with increasing of degradation time was investigated. Futhermore, FCBPBSs and cells were cultured together to study the biocompatibility of FCBPBs indicating good biocompatibility.