2017•Unpublished venueOpen access

Author response: Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

David Moreno‐Delgado, Thor C. Møller, Jeanne Ster, Jesús Giraldo, Damien Maurel, Xavier Rovira, Pauline Scholler, Jurriaan M. Zwier, Julie Perroy, Thierry Durroux, Eric Trinquet, Laurent Prézeau, Philippe Rondard, Jean‐Philippe Pin

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Abstract

Innovative approaches were used to identify the specific pharmacological properties of heterodimeric metabotropic glutamate receptors composed of mGlu2 and mGlu4 subunits, and reveal their existence in a neuronal cell line and in perforant path terminals.

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Key concepts: Metabotropic glutamate receptor, Metabotropic glutamate receptor 2, G protein-coupled receptor, Neuroscience, Receptor, Metabotropic glutamate receptor 4, Metabotropic glutamate receptor 7, Glutamate receptor