Bone Mineral Density T-Scores Derived from CT Attenuation Numbers (Hounsfield Units): Clinical Utility and Correlation with Dual-energy X-ray Absorptiometry.

Background: ) for identifying individuals with osteoporosis. Methods: for this task. Results: of -3.0, corresponding to 110 HU, was 48% sensitive and 91% specific for osteoporosis in the validation group. ROC area under the curve ranged from 0.825 to 0.853 depending on lumbar level assessed. Conclusions: ≤ -3.0 should be referred for additional evaluation. Further research into HU T-scores and clinical correlates may also provide a tool to assess changes in vertebral bone and the relationship to fracture risk across the lifespan.