Effects of Endurance Exercise on the Expression of c-fos Protein in the Central Amygdala of Rat

The purpose of this study is to analyze the effect of endurance exercise on the expres- sion of c-fos protein in central amygdala.Thirty male SD rats were randomly divided into two groups:control group and endurance exercise group.To establish the endurance swimming ex- ercise models in rat,and detect the change of the expression of c-fos positive cells in central a- mygdale by using the method of ABC immunohistoehemistry,then analyze the image and data by imaging analyzing system and statistical software.The result showed that the density of e- fos positive cells in central amygdale were small right after endurance swimming exercise,with- out significant difference as compared with the control group(P0.05);The density of c-fos positive cells in central amygdale were high at 30min,120min and 240rain after endurance swimming exercise,and appeared significant difference as compared with the control group(P0.05);The density of c-fos positive cells gets to the top significantly at 60min(P0.01. It concluded that endurance swimming exercise could affect the expression of e-fos protein in CeA ,and the expression of e-fos protein was timelines.