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SURVEILLANCE OF JAPANESE B ENCEPHALITIS VACCINE ANTIBODY LEVEL BEFORE AND AFTER STRENGTHENING IMMUNIZATION FOR CHILDREN OF 8 MONTHS-6 YEARS OLD IN QIANDONGNAN PREFECTURE

Tang Deliang

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Abstract

[Objective] To understand the Japanese B Encephalitis ( JBE) vaccine antibody level before and after strengthening immunization and provide the scientific basis for controlling JBE in the future. [Methods] Used stratified ran- domization sampling method, the sera samples one month prior and post vaccination were collected and tested by RPHI assay for antibody response. [Results] The antibody positive rate of children raised from 34.71% to 99.16%, the GMT from 1︰3.4 to 1 ︰138.69; the antibody positive rates of the children whose JBE antibody were negative before immunization was 98.78% after inactivated JBE vaccination. The serum antibody level had no difference in the children’s age, sex, race, region and immunity history. The lower the Children antibody’ s level was before the immunity, the higher the children’s antibody positive rate was after the immunity. [Conclusion] The children serum antibody level obviously goes up after strengthening immunization, the immunity success rate which all come to above 96% in each age group. The protection effect is better; the children antibody lev- el is uninfluenced by age, sex, race, region and immunity history, etc. after the immunity.

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What this paper is about

[Objective] To understand the Japanese B Encephalitis ( JBE) vaccine antibody level before and after strengthening immunization and provide the scientific basis for controlling JBE in the future. [Methods] Used stratified ran- domization sampling method, the sera samples one month prior and post vaccination were collected and tested by RPHI assay for antibody response. [Results] The antibody positive rate of children raised from 34.71% to 99.16%, the GMT from 1︰3.4 to 1 ︰138.69; the antibody positive rates of the children whose JBE antibody were negative before immunization was 98.78% after inactivated JBE vaccination. The serum antibody level had no difference in the children’s age, sex, race, region and immunity history. The lower the Children antibody’ s level was before the immunity, the higher the children’s antibody positive rate was after the immunity. [Conclusion] The children serum antibody level obviously goes up after strengthening immunization, the immunity success rate which all come to above 96% in each age group. The protection effect is better; the children antibody lev- el is uninfluenced by age, sex, race, region and immunity history, etc. after the immunity.

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Available abstract

[Objective] To understand the Japanese B Encephalitis ( JBE) vaccine antibody level before and after strengthening immunization and provide the scientific basis for controlling JBE in the future. [Methods] Used stratified ran- domization sampling method, the sera samples one month prior and post vaccination were collected and tested by RPHI assay for antibody response. [Results] The antibody positive rate of children raised from 34.71% to 99.16%, the GMT from 1︰3.4 to 1 ︰138.69; the antibody positive rates of the children whose JBE antibody were negative before immunization was 98.78% after inactivated JBE vaccination. The serum antibody level had no difference in the children’s age, sex, race, region and immunity history. The lower the Children antibody’ s level was before the immunity, the higher the children’s antibody positive rate was after the immunity. [Conclusion] The children serum antibody level obviously goes up after strengthening immunization, the immunity success rate which all come to above 96% in each age group. The protection effect is better; the children antibody lev- el is uninfluenced by age, sex, race, region and immunity history, etc. after the immunity.

Key concepts: Immunity, Immunization, Vaccination, Antibody, Japanese encephalitis, Medicine, Immunology, Herd immunity

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SURVEILLANCE OF JAPANESE B ENCEPHALITIS VACCINE ANTIBODY LEVEL BEFORE AND AFTER STRENGTHENING IMMUNIZATION FOR CHILDREN OF 8 MONTHS-6 YEARS OLD IN QIANDONGNAN PREFECTURE — Research Paper | ScholarLens