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2007•China Practical MedicineRequires access

The correlations between the blood lipids and the stages of atherosclerosis

Tan Shaowen

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Abstract

Objective The correlations between the blood lipids and the stages of atherosclerosis (As) were studied via epidemiological investigations. Methods 60 healthy adults (Group As(-)), 24 atherosclerotic patients with no complication (Group As(+)), 67 atherosclerotic patients with cerebral infarction (Group As(++)) were selected randomly, and some of their serum data were measured including triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDLC), high density lipoprotein cholesterol (HDLC), apolipoprotein AI (ApoAI), apolipoprotein B100 (ApoB100), lipoprotein (a) (LP(a)) and ApoB100/ApoAI ratio. Results As Group As(+) compared with Group As(-), TG, TC, LDLC, ApoB100, LP(a), ApoB100/ApoAI increased (P0.05), and HDLC, ApoAI decreased (P0.05). As Group As(++) compared with Group As(+), ApoB100, LP(a) and ApoB100/ApoAI increased (P0.05). As Group As(++) compared with Group As(-), ApoB100, LP(a) and ApoB100/ApoAI increased significantly (P0.01). Conclusion TG, TC, LDLC, HDLC, ApoAI, ApoB100, LP(a) and ApoB100/ApoAI correlated with the early stage of As, what was more, ApoB100, LP(a) and ApoB100/ApoAI correlated with the late stage of As.

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Objective The correlations between the blood lipids and the stages of atherosclerosis (As) were studied via epidemiological investigations. Methods 60 healthy adults (Group As(-)), 24 atherosclerotic patients with no complication (Group As(+)), 67 atherosclerotic patients with cerebral infarction (Group As(++)) were selected randomly, and some of their serum data were measured including triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDLC), high density lipoprotein cholesterol (HDLC), apolipoprotein AI (ApoAI), apolipoprotein B100 (ApoB100), lipoprotein (a) (LP(a)) and ApoB100/ApoAI ratio. Results As Group As(+) compared with Group As(-), TG, TC, LDLC, ApoB100, LP(a), ApoB100/ApoAI increased (P0.05), and HDLC, ApoAI decreased (P0.05). As Group As(++) compared with Group As(+), ApoB100, LP(a) and ApoB100/ApoAI increased (P0.05). As Group As(++) compared with Group As(-), ApoB100, LP(a) and ApoB100/ApoAI increased significantly (P0.01). Conclusion TG, TC, LDLC, HDLC, ApoAI, ApoB100, LP(a) and ApoB100/ApoAI correlated with the early stage of As, what was more, ApoB100, LP(a) and ApoB100/ApoAI correlated with the late stage of As.

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Available abstract

Objective The correlations between the blood lipids and the stages of atherosclerosis (As) were studied via epidemiological investigations. Methods 60 healthy adults (Group As(-)), 24 atherosclerotic patients with no complication (Group As(+)), 67 atherosclerotic patients with cerebral infarction (Group As(++)) were selected randomly, and some of their serum data were measured including triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDLC), high density lipoprotein cholesterol (HDLC), apolipoprotein AI (ApoAI), apolipoprotein B100 (ApoB100), lipoprotein (a) (LP(a)) and ApoB100/ApoAI ratio. Results As Group As(+) compared with Group As(-), TG, TC, LDLC, ApoB100, LP(a), ApoB100/ApoAI increased (P0.05), and HDLC, ApoAI decreased (P0.05). As Group As(++) compared with Group As(+), ApoB100, LP(a) and ApoB100/ApoAI increased (P0.05). As Group As(++) compared with Group As(-), ApoB100, LP(a) and ApoB100/ApoAI increased significantly (P0.01). Conclusion TG, TC, LDLC, HDLC, ApoAI, ApoB100, LP(a) and ApoB100/ApoAI correlated with the early stage of As, what was more, ApoB100, LP(a) and ApoB100/ApoAI correlated with the late stage of As.

Key concepts: Apolipoprotein B, Medicine, Internal medicine, Triglyceride, Lipoprotein, Lipoprotein(a), Cholesterol, Endocrinology

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