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10.51847/HuvfH6B

Mojtaba Khaksarian, Eskandar Hamidikia, Maryam Sepahvand, Behrooz Farzan

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Abstract

The objective of this study was to assess the antinociceptive activity and acute toxicity of Nectaroscordum koelzi fruit extract in mice. Totally, 90 BALB/c mice were used to determine the antinociceptive effect of the extract using rotarod, tail-flick, and hot plate tests. The acute toxicity was determined at doses of 1, 2, 4, 6 g/kg for 2 days. The maximum non-fatal dose and the LD50 value of N. koelzi fruit extract were 1.97 g/kg and 2.91 g/kg, respectively. The findings showed that in tail-f

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The objective of this study was to assess the antinociceptive activity and acute toxicity of Nectaroscordum koelzi fruit extract in mice. Totally, 90 BALB/c mice were used to determine the antinociceptive effect of the extract using rotarod, tail-flick, and hot plate tests. The acute toxicity was determined at doses of 1, 2, 4, 6 g/kg for 2 days. The maximum non-fatal dose and the LD50 value of N. koelzi fruit extract were 1.97 g/kg and 2.91 g/kg, respectively. The findings showed that in tail-f

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Available abstract

The objective of this study was to assess the antinociceptive activity and acute toxicity of Nectaroscordum koelzi fruit extract in mice. Totally, 90 BALB/c mice were used to determine the antinociceptive effect of the extract using rotarod, tail-flick, and hot plate tests. The acute toxicity was determined at doses of 1, 2, 4, 6 g/kg for 2 days. The maximum non-fatal dose and the LD50 value of N. koelzi fruit extract were 1.97 g/kg and 2.91 g/kg, respectively. The findings showed that in tail-f

Key concepts: Nociception, Hot plate test, Acute toxicity, Toxicity, Analgesic, Pharmacology, Saline, Hot plate

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