Foreign Body Giant Cell Granuloma of the Mandible Subsequent to Endodontic Surgery

ABSTRACT Granuloma formation is a specific type of chronic inflammation initiated by infectious and noninfectious agents with an aggregation of multinucleated giant cells. Foreign body giant cells (FBGCs) most commonly observed at the tissue/material interface where the size of foreign particulate is too large to permit macrophage phagocytosis. In this context, adherent macrophages and FBGCs constitute the foreign body reaction. Foreign-body giant cell granulomas have been reported to cause clinical symptoms from months to decades after a surgical procedure and can present with a variety of symptoms, usually on the basis of location. Foreign-body giant cell granulomas in the mandible are rare lesions, here we report a case of FBGC granuloma in the mandible that developed after endodontic treatment. How to cite this article Rai H, Shaila M, Ghosh G, Suhasini PD. Foreign Body Giant Cell Granuloma of the Mandible Subsequent to Endodontic Surgery. J Contemp Dent 2015;5(3):178-180.