В. И. Поткин, С. К. Петкевич, П. В. Курман
Abstract
Abstract Thienyl trichloroallyl ketone (I), a synthetic equivalent of β‐chlorovinyl ketones, reacts with hydroxylamine to an intermediate dichloromethyl‐substituted isoxazole which upon reaction with a second hydroxylamine molecule affords the hydoxyiminomethyl‐substituted isoxazole (II).
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Abstract Thienyl trichloroallyl ketone (I), a synthetic equivalent of β‐chlorovinyl ketones, reacts with hydroxylamine to an intermediate dichloromethyl‐substituted isoxazole which upon reaction with a second hydroxylamine molecule affords the hydoxyiminomethyl‐substituted isoxazole (II).
Key concepts: Isoxazole, Hydroxylamine, Chemistry, Ketone, Medicinal chemistry, Organic chemistry