ChemInform Abstract: Organocatalysis for the Synthesis of Optically Active β‐Malonophosphonates.
Prashant B. Thorat, Santosh V. Goswami, Rupali L. Magar, Sudhakar R. Bhusare
Abstract
Prashant B. Thorat, Santosh V. Goswami, Rupali L. Magar, Sudhakar R. Bhusare
Abstract
Abstract Phospha—Michael addition of P(O—Et)3 to benzylidenemalononitriles (I) in the presence of a proline‐based organocatalyst represents one of the most straightforward routes for the synthesis of optically active β‐malonophosphonates (III) (13 examples).
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Abstract Phospha—Michael addition of P(O—Et)3 to benzylidenemalononitriles (I) in the presence of a proline‐based organocatalyst represents one of the most straightforward routes for the synthesis of optically active β‐malonophosphonates (III) (13 examples).
Key concepts: Chemistry, Optically active, Organocatalysis, Proline, Michael reaction, Combinatorial chemistry, Enantioselective synthesis, Organic chemistry