A Convenient, One-Step Synthesis of Optically Active Tertiary Aminonaphthol and Its Applications in the Highly Enantioselective Alkenylations of Aldehydes
Jian‐Xin Ji, Liqin Qiu, Chiu Wing Yip, Albert S. C. Chan
Abstract
Jian‐Xin Ji, Liqin Qiu, Chiu Wing Yip, Albert S. C. Chan
Abstract
Optically active tertiary aminonaphthol 1 was obtained by a new, convenient procedure and was found to catalyze the enantioselective alkenylation of various aldehydes with high ee values, which provides a practical method for the synthesis of chiral (E)- allyl alcohols.
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Optically active tertiary aminonaphthol 1 was obtained by a new, convenient procedure and was found to catalyze the enantioselective alkenylation of various aldehydes with high ee values, which provides a practical method for the synthesis of chiral (E)- allyl alcohols.
Key concepts: Enantioselective synthesis, Optically active, Chemistry, Organic chemistry, Combinatorial chemistry, Tertiary alcohols, Catalysis