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In vitroProtein Refolding

Jeffrey L. Cleland, Daniel I. C. Wang

Abstract

This chapter contains sections titled: Introduction Folding in Eukaryotic and Prokaryotic Hosts Inclusion Body Formation Effect of Folding Mutations Molecular Chaperones Synthetic Folding Aids Models of in vitro Protein Refolding In vitro Refolding Dependence on Denaturant Concentration Temperature Effects on Refolding Aggregation During Refolding Summary References

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Available abstract

Key concepts: In vitro, Folding (DSP implementation), Protein folding, Chemistry, Chaperone (clinical), Protein aggregation, Biophysics, Biochemistry