Efficacy of Stereotactic Minimally Invasive Procedures Removing Intracranial Hemotoma in Patients with Intracerebral Hemorrhage

[ Abstract]Objective:To explore the efficacy of stereotactic minimally invasive procedures removing intracranial hemotoma in patients with intracerebral hemorrhage. Methods:60 patients with cerebral hemorrhage were divided into minimally invasive surgery group and drug treatment group,30 cases in each group. Hematoma removal time,compound mannitol dosage,and hospital stays of two groups pa-tients were compared. Neurological deficit( NIHSS)score of the two groups of patients were recorded at admission and discharge. The serum levels of C reactive protein( CRP)in the two groups were measured by immune transmission turbidity method at admission,at 1 d after minimally invasive sur-gery or at the same time point of drug treatment group. Results:Hematoma clearance time,hospitali-zation time and compound mannitol dosage in minimally invasive surgery group were less than those of the drug treatment group,and the difference was statistically significant( P ﹤0. 05). There were no statistically significant differences in serum CRP level and NIHSS between the two groups at admission ( P﹥0 . 05 ). The serum CRP level in minimally invasive surgery group at 1 d after minimally invasive surgery was significantly higher than before surgery and than that of drug treatment group at the same time point( P﹤0 . 05 ),while there was no statistically significant differences in the serum CRP level between at admission and at the same time point of minimally invasive surgery( P﹥0 . 05 ). At the time of discharge,the serum CRP level of the two groups was in the normal value(P﹥0. 05),but the ser-um CRP level in minimally invasive surgery group was significantly higher than that of the drug treat-ment group(P﹤0. 05). When discharged,NIHSS score in the two groups of patients with were lower than at admission,which decreased more significantly in minimally invasive surgery group,and the difference was statistically significant( P﹤0 . 05 ). Conclusions:Stereotactic minimally invasive pro-cedures can reduce the damage degree of brain tissue,curative effect is better than drug treatment,and the level of serum CRP was increased at 1 d after minimally invasive surgery.