2019Vacuum and Surface ScienceOpen access

Biomaterial Surface and Interface Analysis by Means of Time-of-Flight Secondary Ion Mass Spectrometry

Satoka Aoyagi

Open full text 1 citations

Abstract

Thanks to the development of gas cluster ion beam (GCIB) such as an Ar cluster ion beam, the application of TOF-SIMS has been growing, especially in biological fields. GCIB enables sputtering of soft materials including biological cells and tissues to provide 3D images. The features of the latest TOF-SIMS related techniques and applications of TOF-SIMS into biological samples, such as hair, skin, cells, and tissues, and bio-model samples for biomolecule investigation are briefly introduced in this article.

Open-access reader

About this research paper

What this paper is about

Thanks to the development of gas cluster ion beam (GCIB) such as an Ar cluster ion beam, the application of TOF-SIMS has been growing, especially in biological fields. GCIB enables sputtering of soft materials including biological cells and tissues to provide 3D images. The features of the latest TOF-SIMS related techniques and applications of TOF-SIMS into biological samples, such as hair, skin, cells, and tissues, and bio-model samples for biomolecule investigation are briefly introduced in this article.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Thanks to the development of gas cluster ion beam (GCIB) such as an Ar cluster ion beam, the application of TOF-SIMS has been growing, especially in biological fields. GCIB enables sputtering of soft materials including biological cells and tissues to provide 3D images. The features of the latest TOF-SIMS related techniques and applications of TOF-SIMS into biological samples, such as hair, skin, cells, and tissues, and bio-model samples for biomolecule investigation are briefly introduced in this article.

Key concepts: Secondary ion mass spectrometry, Mass spectrometry, Biomaterial, Interface (matter), Time of flight, Analytical Chemistry (journal), Materials science, Chemistry

Related papers

Back to paper searchBrowse research topicsOriginal source
Biomaterial Surface and Interface Analysis by Means of Time-of-Flight Secondary Ion Mass Spectrometry — Research Paper | ScholarLens