ScholarLens Back to search
2018•GSC Biological and Pharmaceutical SciencesOpen access

Spectrophotometric method for dissolution analysis of pioglitazone from capsules

Kalpana Patankar-Jain, Parag Gadkari, Pushkar Pradhan

Open full text 2 citations

Abstract

Pioglitazone, an anti-diabetic molecule have been analyzed from a marketed capsule consisting of glimepiride and pioglitazone using spectrophotometric method. The method was developed at 270 nm using 0.1 N HCl as diluent. The method was found to be highly specific for pioglitazone in presence of glimepiride and other constituents of the capsule. The developed method is simple, precise, robust and stands validated as per ICH guidelines.

Open-access reader

About this research paper

What this paper is about

Pioglitazone, an anti-diabetic molecule have been analyzed from a marketed capsule consisting of glimepiride and pioglitazone using spectrophotometric method. The method was developed at 270 nm using 0.1 N HCl as diluent. The method was found to be highly specific for pioglitazone in presence of glimepiride and other constituents of the capsule. The developed method is simple, precise, robust and stands validated as per ICH guidelines.

Why it matters

OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Pioglitazone, an anti-diabetic molecule have been analyzed from a marketed capsule consisting of glimepiride and pioglitazone using spectrophotometric method. The method was developed at 270 nm using 0.1 N HCl as diluent. The method was found to be highly specific for pioglitazone in presence of glimepiride and other constituents of the capsule. The developed method is simple, precise, robust and stands validated as per ICH guidelines.

Key concepts: Pioglitazone, Glimepiride, Diluent, Capsule, Dissolution, Chromatography, Chemistry, Nuclear chemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Spectrophotometric method for dissolution analysis of pioglitazone from capsules — Research Paper | ScholarLens