2018•Bioorganic & Medicinal Chemistry LettersOpen access

Synthesis and SAR studies of novel benzodiazepinedione-based inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB)

Jeffrey J. Letourneau, Ilana L. Stroke, David W. Hilbert, Andrew G. Cole, Laurie J. Sturzenbecker, Brett A. Marinelli, Jorge G. Quintero, Joan E. Sabalski, Yanfang Li, Linh Ma, Igor V. Pechik, Philip D. Stein, Maria L. Webb

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Key concepts: Clostridium difficile, Clostridium difficile toxin A, Toxin, Chemistry, Clostridium difficile toxin B, Microbiology, Clostridium, Hamster