2005•Journal of Clinical MicrobiologyOpen access

Clonal Spread of a Clostridium difficile Strain with a Complete Set of Toxin A, Toxin B, and Binary Toxin Genes among Polish Patients with Clostridium difficile -Associated Diarrhea

Hanna Pituch, Deborah Kreft, Piotr Obuch-Woszczatyński, Dorota Wultańska, F Meisel-Mikołajczyk, Mirosław Łuczak, Alex van Belkum

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Abstract

Clinically relevant Clostridium difficile strains usually produce toxins A and B. Some C. difficile strains can produce an additional binary toxin. We report clonality among five strains carrying all toxin genes from Polish patients with C. difficile-associated diarrhea. In another strain, possible recombination between binary toxin genes is documented.

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Key concepts: Clostridium difficile, Pore-forming toxin, Toxin, Clostridium difficile toxin A, Microbiology, Clostridium difficile toxin B, Clostridiaceae, Strain (injury)