Improved Quality and Number of Platelet Count in Apheresis-Platelet Concentrate> Buffy Coat-Platelet Concentrate & Platelet Rich Plasma-Platelet Concentrate, Assessed by Study of Quality Parameters in 119 Units of Platelet Concentrate

Background: A successful transfusion requires whole blood to be separated into components that can be removed based on specific gravity via centrifugation.Platelet quality can then be determined using in vitro analysis of the following parameters: volume, swirling, platelet count (PLC), WBC count, and pH.This study was performed to assess the platelet concentrate (PC) quality obtained by three different methods as per the recommended quality norms at our blood bank.Design: Random donor platelets by platelet rich plasma-platelet concentrate (PRP-PC), Buffy coat poor-platelet concentrate (BC-PC), and single donor platelets by Apheresis-PC (APH-PC) were prepared and examined.A total of 119units (58 BC-PC, 36 PRP-PC, and 25 APH-PC) were assessed using the following parameters: volume, swirling, PLC, and pH. Results:The mean volume of PRP-PC, BC-PC and APH-PC was 73.04±4.35ml,75.01±3.27mland 272±2.98mland ranged from 68-88ml, 55-82ml and 263-276ml, respectively.The mean PLC of PRP-PC, BC-PC, and APH-PC were 7.95±2.31×1010 / unit, 66±2.29×10 10 /unit, and 4.19±0.45×1011 /unit and ranged from 4-13.6×10 10 /unit, 5.4-15.4×10 10 /unit and 3-4.7×10 11 /unit, respectively.The mean pH was 6.23±0.15(range: 6.0-6.8).No significant difference was observed among the three PC types.All units had a pH well above the recommended norm.PRP-PC and BC-PC units were comparable in terms of swirling, PLC per unit, and pH (Table 1).