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2018•Acta Pharmacologica SinicaOpen access

18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway

Shouyan Wu, Shichao Cui, Le Wang, Yiting Zhang, Xiaoxia Yan, Henglei Lu, Guozhen Xing, Jin Ren, Likun Gong

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Key concepts: Cholestasis, Bile acid, CYP27A1, CYP8B1, Cholesterol 7 alpha-hydroxylase, Farnesoid X receptor, Liver injury, Chemistry

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18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway — Research Paper | ScholarLens