2000•Molecular CellOpen access

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Bryan Goodwin, Stacey A. Jones, Roger R. Price, Michael A. Watson, David D. McKee, Linda B. Moore, Cristin M. Galardi, Joan G. Wilson, Michael C. Lewis, Matthew E. Roth, Patrick Maloney, Timothy M. Willson, Steven A. Kliewer

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Key concepts: Farnesoid X receptor, Small heterodimer partner, Cholesterol 7 alpha-hydroxylase, G protein-coupled bile acid receptor, Biology, Bile acid, Nuclear receptor, Liver receptor homolog-1