2018•Journal of Clinical HypertensionOpen access
Arterial stiffness in elderly patients with normotension and hypertension in Brazil
Guilherme Silva de Mendonça, Denis Fabiano de Souza, Ana Claudia Brunelli, Cristina Ila de Oliveira Peres, Ercilhana Gonçalves Batista Freitas, Gabriela Nolasco Lacerda, Michelle Caixeta Naves Dorneles, Aldo J. Peixoto, Sebastião Rodrigues Ferreira Filho
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Abstract
Data on arterial stiffness in older populations, according to blood pressure (BP) levels, are scarce in Brazil. The objective of this study was to establish reference values for core measures of arterial stiffness, including carotid-femoral pulse wave velocity (cf-PWV) and aortic augmentation index (AIx), in a cohort of older individuals with normotension (NT) and hypertension. Cross-sectional analysis was performed with applanation tonometry data from 1192 patients aged 60 years or older. The authors classified patients according to their BP levels as having NT, controlled hypertension (CH), and uncontrolled hypertension (UH). The cf-PWV values were 9.11 ± 0.16 m/s (NT), 9.12 ± 0.18 m/s (CH), and 9.42 ± 2.2 m/s (UH) (P < 0.005; UH vs NT and CH). The AIx was 33.3% for the entire cohort and similar across all groups. The cf-PWV increased with age but reached a ceiling at 75 years. Compared with men, women had a higher AIx but similar cf-PWV levels. In conclusion, the markers of arterial stiffness were similar among individuals with NT/CH and higher among individuals with UH.