Towards the Isolation and Identification of Antimicrobial Compounds Produced by Bacillus subtilis
Kevin Dold
Abstract
Kevin Dold
Abstract
A close relative or strain of Bacillus subtilis isolated from local soil samples was previously shown to inhibit the growth of E. coli and S. epidermidis when grown competitively using a cross streak method. B. Subtilis is the most widely studied Gram-positive bacterium. Organic extracts from this bacteria has been tested against several ESKAPE pathogens using both direct application and TLC–bioautography. Further work to isolate and test the antimicrobial compounds produced by this bacteria closely related to Bacillus subtilis will be discussed.
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A close relative or strain of Bacillus subtilis isolated from local soil samples was previously shown to inhibit the growth of E. coli and S. epidermidis when grown competitively using a cross streak method. B. Subtilis is the most widely studied Gram-positive bacterium. Organic extracts from this bacteria has been tested against several ESKAPE pathogens using both direct application and TLC–bioautography. Further work to isolate and test the antimicrobial compounds produced by this bacteria closely related to Bacillus subtilis will be discussed.
Key concepts: Bacillus subtilis, Isolation (microbiology), Identification (biology), Antimicrobial, Microbiology, Biology, Bacteria, Genetics