Atypical presentation of chronic myeloid leukemia with visual disturbance
Rachana Chennamaneni, Stalin Bala, Sadashivudu Gundeti, Meher Lakshmi
Abstract
Rachana Chennamaneni, Stalin Bala, Sadashivudu Gundeti, Meher Lakshmi
Abstract
Chronic myeloid leukemia (CML) is a clonal hematopoietic disorder characterized by a reciprocal translocation between chromosome 9 and 22 resulting in bcr-abl1 fusion gene. Patients usually present with symptoms of anemia, splenomegaly, and hyperleukocytosis. Initial presentation with visual disturbance, without other symptoms, is rare in CML. No specific treatment has been described for ocular lesions in leukemia. Treating the underlying malignancy would aid in resolution of the symptoms. We report a case of CML presenting with retinal hemorrhages.
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Chronic myeloid leukemia (CML) is a clonal hematopoietic disorder characterized by a reciprocal translocation between chromosome 9 and 22 resulting in bcr-abl1 fusion gene. Patients usually present with symptoms of anemia, splenomegaly, and hyperleukocytosis. Initial presentation with visual disturbance, without other symptoms, is rare in CML. No specific treatment has been described for ocular lesions in leukemia. Treating the underlying malignancy would aid in resolution of the symptoms. We report a case of CML presenting with retinal hemorrhages.
Key concepts: Medicine, Myeloid leukemia, Visual Disturbance, Presentation (obstetrics), Chromosomal translocation, Anemia, Malignancy, Dermatology