2017•European Journal of Medicinal ChemistryRequires access

Investigating the structure-activity relationships of N’-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against Trypanosoma cruzi to design novel active compounds

Fanny Palace‐Berl, Kerly Fernanda Mesquita Pasqualoto, Bianca Zingales, Carolina Borsoi Moraes, Mariana Bury, Caio Haddad Franco, Adelson Lopes da Silva Neto, João Sussumu Murayama, Solange Lessa Nunes, Marcelo Nunes Silva, Leoberto Costa Tavares

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Key concepts: Benznidazole, Nitrofuran, Trypanosoma cruzi, Amastigote, Nifurtimox, Chagas disease, Chemistry, Antiprotozoal